Advanced Purification Solutions for API and Drug Development
The production of Active Pharmaceutical Ingredients (APIs) requires highly efficient and reliable purification processes to ensure product quality, safety, and regulatory compliance.
APIs are manufactured using a variety of methods, including:
- Chemical synthesis
- Semi-synthetic production
- Fermentation (biotechnology)
- Extraction from natural sources
- Cell culture processes
- Enzymatic and biocatalytic methods
Across all these production routes, impurity removal is a critical step during API development and manufacturing.
Impurities may originate from:
- Raw materials
- Reaction by-products
- Residual catalysts
- Process solvents
To achieve the required purity levels, manufacturers combine multiple API purification techniques, such as:
- Filtration
- Centrifugation
- Crystallization
- Distillation
- Liquid-liquid extraction
- Chromatography
- Precipitation
- Ultrafiltration
- Drying and evaporation
- Adsorption
Micro/Mesoporous grades
NORIT SX range
- Choice of capacities for smaller and larger impurities
- Very high, tightly specified purity
- Excellent filterability
Powdered Activated Carbon
Mesoporous grades
NORIT C-CARBON grades
- High capacity for larger impurities
- Very high, tightly specified purity
- Excellent filterability
Powdered Activated Carbon
Ultrapure powdered grade
NORIT SX PLUS LC
- extremely high purity by unique process
- high capacities for smaller and larger impurities
Powdered Activated Carbon
Ultrapure granular grade
NORIT ROX 0.8
- High capacities for smaller and larger impurities
- Extremely high purity
- Very high hardness
